In this video, Dr. Perlmutter talks at the Buck Institute for about 20 minutes about the important role of the gut microbiome…
They he and Dr. Dale Bredesen answers audience questions which covers topic like …
- Cholesterol and fat. Cholesterol is not bad. It plays an important role in the body in terms of supply life-sustaining nutrients to the cells. What you eat does not correlate well with the cholesterol levels in the blood, because most of the blood cholesterol is made by your liver and not from the food. No correlation between intake of fat and cardiovascular disease. But trans fat is bad.
- Statins not so good because they decrease the production of Co-Q10, a brain antioxidant. While statin might have a good side such as its anti-inflamatory effects, it maybe out-weight by the bad side.
- Supplements Dr. Perlmutter believe can be beneficial are vitamin D, B vitamins, DHA, and NAC. Have your levels measured and try to get them into the “optimal” range instead of just the “normal” range. There is mention that Omega-3 (along with vitamin D) enhance ability of macrophages to phagocytosize amyloid beta in the brain. [reference]
- Caffeine and coffee. Some neuroprotective effects of caffeine. Also phytophytophenols in coffee itself. Coffee drinkers are at lower risk for Alzheimer’s.
- APOE4 “Alzheimer’s Gene”. Perlmutter believes a high fat diet outweighs some of the negative effects of fat on APOE4 carriers.
- They both believe in eating organics and non-GMO.
- Perlmutter believe that we should avoid gluten (even if we are not diagnosed with celiac disease), because gluten increase leakiness of gut and thereby increase inflammation. Also gluten foods are typically high carb foods, which we should avoid eating anyways.
- Alcohol in and of itself is a neurotoxin. But small amount is okay. A glass of red wine has some upsides that would allow it in the diet.