Magnesium is a very important mineral for the body in general, utilized in more than 300 enzymes. And many people are deficient in magnesium.
Article on drperlmutter.com writes about Magnesium Threonate …
“critical player in the activation of nerve channels that are involved in synaptic plasticity”
Unfortunately, magnesium in not readily absorb via the gut (perhaps 35% to 45%). Magnesium citrate is the best absorbed form. But it can be absorbed via the skin such as in Epsom salt baths (magnesium sulphate). [reference]
If you are taking magnesium for the brain, magnesium threonate is one form that can cross the blood brain barrier, while most other forms can not.
LiveTo100.com writes …
“Magnesium threonate is the only form known to readily cross the blood-brain barrier and penetrate the mitochondrial membrane to improve brain function.”
If you are taking magnesium for relaxation or sleep, magnesium glycinate may be help because glycine helps with sleep.
Dr. Emily Deans talks about magnesium in “Episode 13 – Dr. Emily Deans on nutrition and mental health” of Chris Kresser’s podcast.
She writes in her article ..
“… calcium and glutamate are excitatory, and in excess, toxic. They activate the NMDA receptor. Magnesium can sit on the NMDA receptor without activating it, like a guard at the gate. Therefore, if we are deficient in magnesium, there’s no guard. Calcium and glutamate can activate the receptor like there is no tomorrow. In the long term, this damages the neurons, eventually leading to cell death. In the brain, that is not an easy situation to reverse or remedy.”
Magnesium helps converting the amino acid trytophan into the neurotransmitter serotonin.
Magnesium is a relaxation mineral and helps mitigate stress.